• No. 5-19-03A, Jalan Medan P8A, Seksyen 9, Bangi, Selangor
  • 0179200969
Hempedu Bumi

Hempedu Bumi the local name for Andrographis paniculata is a small annual herb extremely bitter in taste in all parts of the plant. Traditionally, this plant was used as a treatment for fever, common cold, respiratory infection, diarrhea, inflammation and detoxication.

Andrographolide is a major bioactive phytoconstituent found in Hempedu bumi exhibits a broad range of biological activities, such as anti-inflammatory, antibacterial, antitumor, antidiabetic, antimalarial, and hepatoprotective.

Hempedu Bumi nama tempatan untuk Andrographis paniculata adalah herba tahunan kecil amat pahit dalam semua bahagian tumbuhan. Secara tradisional, tumbuhan ini telah digunakan sebagai rawatan untuk demam, selsema, jangkitan pernafasan, cirit-birit, radang dan detoxication. Andrographolide adalah phytoconstituent bioaktif utama yang terdapat dalam Hempedu bumi mempamerkan pelbagai aktiviti biologi, seperti anti-radang, anti-bakteria, anti-tumor, antidiabetik, malaria, dan hepatoprotective.

Content / Kandungan

Each 380mg vegetable capsule contains 60mg of
Folium Andrographis Paniculata (Hempedu Bumi) extract.

Setiap kapsul 380mg sayur-sayuran mengandungi ekstrak
60mg Folium Andrographis Paniculata (Hempedu Bumi).

Targeted consumers: Men & Women

Anticipated dose:

Andrographis paniculata extract (120mg/day or 2 capsules daily)

Purpose:

Traditionally used for relieving headache

Safety / Keselamatan

Acute toxicity

Oral single dose using Hempedu bumi aqueous extract on female Sprague Dawley rats showed no toxic effect on the parameters observed (behaviors, body weight & food intake). No death were found throughout 14 days study period. Necropsy revealed no significant abnormality. LD50 >2000mg/kg (Teh BP et. al, 2012).

Kajian toksikologi Sub Ketoksikan akut 

Dos tunggal lisan menggunakan Hempedu bumi ekstrak akueus pada perempuan tikus Sprague Dawley tidak menunjukkan kesan toksik kepada parameter diperhatikan (tingkah laku, berat badan dan pengambilan makanan). Tiada kematian telah didapati 14 hari tempoh kajian. Pembedahan mayat menurunkan sebarang keabnormalan yang ketara. LD50> 2000mg / kg (Teh BP et. Al, 2012).

Certificate Of Analysis (COA)
  • Free from pathogenic microbes
  • Free from heavy metal poisoning
Scientific Info on Efficacy / Keberkesanan

Anti-oxidant activity

Laboratory studies have found that constituents contained in Hempedu bumi have antioxidant properties, including neuroprotection, nephroprotection and also hepatic protection by decreasing lipid peroxidation (Das et. Al, 2009)

Anti-tumor activity

 The constituent andrographolide is reported in laboratory studies to have anti-tumor activity in gastric cancer, liver cancer, lung cancer and breast cancer (Trivedi et. al, 2009).

Treatment for fever

 In clinical studies, A. paniculata supplements have been found to decrease severity and duration of upper respiratory tract infection (Gabriellian et. al, 2002). Improvements in muscle pain, cough, throat symptoms, headache, nasal  symptoms and temperature have been also been reported (Melchior et. al, 2000)

Anti-oksida

Kajian makmal telah mendapati bahawa juzuk yang terkandung dalam Hempedu bumi mempunyai sifat antioksidan, termasuk neuroprotection, nephroprotection dan perlindungan juga hepatik dengan mengurangkan pengoksidaan lipid (Das et. Al, 2009)

Anti-tumor  

Andrographolide konstituen dilaporkan dalam kajian makmal mempunyai aktiviti anti-tumor dalam kanser perut, kanser hati, kanser paru-paru dan kanser payudara (Trivedi et. Al, 2009).

Rawatan untuk demam  

Dalam kajian klinikal, makanan tambahan A. paniculata yang untuk mengurangkan keterukan dan tempoh jangkitan saluran pernafasan atas (Gabriellian et. Al, 2002). Penambahbaikan dalam sakit otot, batuk, gejala tekak, sakit kepala, gejala hidung dan suhu telah juga telah dilaporkan (Melchior et. Al, 2000)